Cisco ISE API Unauthenticated Remote Code Execution Vulnerability
- Severity
- Critical10CVSS 3.1, Critical
- EPSS
- 98%
- Published
- 25 Jun 2025
- Updated
- 17 Jun 2026
Description
Title, description and vendor guidance are quoted from the source records.
A vulnerability in a specific API of Cisco ISE and Cisco ISE-PIC could allow an unauthenticated, remote attacker to execute arbitrary code on the underlying operating system as root. The attacker does not require any valid credentials to exploit this vulnerability. This vulnerability is due to insufficient validation of user-supplied input. An attacker could exploit this vulnerability by submitting a crafted API request. A successful exploit could allow the attacker to obtain root privileges on an affected device.
Weakness: CWE-74
Known exploited
Added to CISA KEV on 28 Jul 2025
Federal remediation due date: 18 Aug 2025
Required action: Apply mitigations per vendor instructions, follow applicable BOD 22-01 guidance for cloud services, or discontinue use of the product if mitigations are unavailable.
Exploit prediction
98% probability of exploitation in the next 30 days (percentile 100%).
CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:C/C:H/I:H/A:H
Affected products
Patcharo shows this vulnerability for information but does not match versions for this product yet.
- Cisco Cisco Identity Services Engine Software · 3.3.0, 3.3 Patch 2, 3.3 Patch 1, 3.3 Patch 3, 3.4.0, 3.3 Patch 4, 3.4 Patch 1, 3.3 Patch 5, 3.3 Patch 6
References
- cisco-sa-ise-unauth-rce-ZAd2GnJ6(opens in a new tab)
- https://www.cisa.gov/known-exploited-vulnerabilities-catalog?field_cve=CVE-2025-20281(opens in a new tab)
- https://www.zerodayinitiative.com/blog/2025/7/24/cve-2025-20281-cisco-ise-api-unauthenticated-remote-code-execution-vulnerability(opens in a new tab)
Provenance
Every fact on this page comes from the sources below. Nothing is written by an AI.
- Cisco (CVE record)
- Cisco (CVE record) · 27 Sept 2026, 23:46 UTC · Parser patcharo-cve5/1.1.0
- CISA Known Exploited Vulnerabilities
- CISA Known Exploited Vulnerabilities · 27 Sept 2026, 23:42 UTC · Parser patcharo-kev/1.0.0
- NVD
- NVD · 27 Sept 2026, 23:44 UTC · Parser patcharo-nvd/1.0.0
- FIRST EPSS
- FIRST EPSS · 27 Sept 2026, 23:46 UTC · Parser patcharo-epss/1.0.0
Last verified: 28 Sept 2026, 02:31 UTC